Prognostic Value of Computed Tomography-Detected Extramural Venous Invasion to Predict Disease-Free Survival in Patients With Gastric Cancer
| Autor: | Hak-Jin Kim, Hyun Jung Baek, Jun Woo Lee, Tae Un Kim, Hyun Sung Kim, Tae Yong Jeon, Suk Kim, Ga Jin Han, Nam Kyung Lee, Do Yoon Park |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
Adult
Male medicine.medical_specialty Pathology Multivariate analysis Lymphovascular invasion Kaplan-Meier Estimate Gastroenterology Disease-Free Survival 030218 nuclear medicine & medical imaging 03 medical and health sciences 0302 clinical medicine Stomach Neoplasms Internal medicine Medicine Humans Radiology Nuclear Medicine and imaging In patient Neoplasm Invasiveness Stage (cooking) Pathological Aged Proportional Hazards Models Retrospective Studies Aged 80 and over business.industry Proportional hazards model Cancer Retrospective cohort study Middle Aged medicine.disease Prognosis 030220 oncology & carcinogenesis Female business Tomography X-Ray Computed |
| Zdroj: | Journal of computer assisted tomography. 41(3) |
| ISSN: | 1532-3145 |
| Popis: | Objective This study aimed to investigate whether there is a correlation between the computed tomography-detected extramural venous invasion (ctEMVI) and disease-free survival (DFS) in patients with gastric cancer using pathologic lymphovascular invasion as a reference standard. Methods We retrospectively reviewed 153 patients with gastric cancer who underwent computed tomography during 1 year. Differences in pathological findings between the ctEMVI-positive and ctEMVI-negative groups were analyzed. Disease-free survival was estimated using the Kaplan-Meier method. Factors affecting DFS were analyzed with the Cox proportional hazard model. Results The ctEMVI-positive group was correlated more with lymphovascular invasion (P = 0.008). The 1- and 2-year DFS rates were 92% and 80%, respectively, in the ctEMVI-negative group, but 77% and 54%, respectively, in the ctEMVI-positive group. A multivariate analysis revealed that tumor size, ctEMVI, and pathological stage remained associated with DFS (Ps = 0.037, 0.015, and 0.002, respectively). Conclusions The ctEMVI was an independent prognostic factor for worse DFS in patients with gastric cancer. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|