Orthogonal N,N-deprotection strategies of beta-amino esters
| Autor: | Massimo Gianotti, Andrew D. Smith, Steven D. Bull, Stephen G. Davies, Peter M. Kelly |
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| Jazyk: | angličtina |
| Rok vydání: | 2016 |
| Předmět: | |
| Popis: | β-Amino esters derived from the stereoselective conjugate addition of homochiral lithium N-benzyl-N-α-methyl-4-methoxybenzylamide to α,β-unsaturated esters may be orthogonally mono-N-deprotected under either oxidative or acid-promoted reaction conditions. Further oxidative deprotection affords β-amino acids or β-lactams. |
| Databáze: | OpenAIRE |
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