Calcium phosphate materials containing alumina: Raman spectroscopical, histological, and ultrastructural study

Autor: Alessandro Bertoluzza, M. Morocutti, V. Ottani, Alessandro Ruggeri, R. Simoni, Anna Tinti
Rok vydání: 1991
Předmět:
Zdroj: Journal of Biomedical Materials Research. 25:23-38
ISSN: 1097-4636
0021-9304
DOI: 10.1002/jbm.820250103
Popis: Variable alumina quantities were added to two types of calcium phosphate materials-hydroxyapatite ceramics with Ca/P = 1.67 and calcium metaphosphate glass with Ca/P = 1--in order to increase their mechanical properties. Raman spectroscopy shows that alumina interacts with the phosphate group of these materials, while thermomechanical analysis shows that their elastic modulus has a value similar to that of bone. Histological sections demonstrate that the surface in close contact with ceramic materials shows a good integration between bone and biomaterial. All ceramic specimens are penetrated by well-stained, presumably glycoprotein, matrix, that consistently forms a thin network in close contact with the implant. After 6 weeks bone growing on both ceramic and glass shows signs of maturation with a lamellar structure and an apparently normal mineralization. In the case of the glass, inside this newly formed bone, were often observed two layers, the internal one showing a well defined lamellar structure.
Databáze: OpenAIRE