Electrochemical Characterizations of four Main Redox-metabolites ofPseudomonas Aeruginosa
| Autor: | George G. Malliaras, Maxime Gougis, Julie Oziat, Pascal Mailley |
|---|---|
| Přispěvatelé: | Commissariat à l'énergie atomique et aux énergies alternatives - Laboratoire d'Electronique et de Technologie de l'Information (CEA-LETI), Direction de Recherche Technologique (CEA) (DRT (CEA)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA), Ecole Natl Super Mines, Dept Bioelect, Ecole Natl Super Mines Gardanne, ANR-11-LABX-0003,ARCANE,Grenoble, une chimie bio-motivée(2011) |
| Rok vydání: | 2017 |
| Předmět: |
0301 basic medicine
Electrochemical detection medicine.disease_cause Electrochemistry 01 natural sciences Redox Analytical Chemistry [SPI]Engineering Sciences [physics] 03 medical and health sciences chemistry.chemical_compound Pyocyanin medicine Metabolites detection biology 010405 organic chemistry Pseudomonas aeruginosa Quorum Sensing biology.organism_classification Combinatorial chemistry 0104 chemical sciences Pseudomonas quinolone signal Quorum sensing 030104 developmental biology chemistry Bacteria |
| Zdroj: | Electroanalysis Electroanalysis, 2017, 29 (5), pp.1332-1340. ⟨10.1002/elan.201600799⟩ Electroanalysis, Wiley-VCH Verlag, 2017, 29 (5), pp.1332-1340. ⟨10.1002/elan.201600799⟩ |
| ISSN: | 1040-0397 1521-4109 |
| DOI: | 10.1002/elan.201600799 |
| Popis: | © 2017 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim Bacterial identification is of first importance in clinic nowadays. For few years, electrochemistry appears as a reliable route for characterizations outside of laboratories. Nowadays, researchers mainly focus on the opportunistic pathogen Pseudomonas aeruginosa because of its production of the Pyocyanin toxin which has an electrochemical case study behavior. Other P. aeruginosa secreted molecules are also studied in a lesser extent. This work deals with the systematic electrochemical characterizations in aprotic and protic solvents of 4 main metabolites of this bacterium in the view of multispecies detection of P. aeruginosa. We report here the behavior of the 2-Heptyl-4(1H)-quinolone (HHQ), Pseudomonas Quinolone Signal (PQS), Pyocyanin (PYO) and the 2′aminoacetophenone (2-AA). All the mentioned species are clearly visible by using electrochemical techniques (cyclic and square wave voltammetries). The 2 most suitable species for electrochemical detection appear to be PQS and PYO because of their detection at low potential. |
| Databáze: | OpenAIRE |
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