Associations between Dietary Patterns and Bile Acids—Results from a Cross-Sectional Study in Vegans and Omnivores
Autor: | Hanns-Ulrich Marschall, Alfonso Lampen, Iris Trefflich, Romina di Giuseppe, Marcus Ståhlman, Andreas Michalsen, Klaus Abraham, Cornelia Weikert |
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Jazyk: | angličtina |
Rok vydání: | 2019 |
Předmět: |
0301 basic medicine
Adult Dietary Fiber Male Diet Vegan Meat Cross-sectional study Glycine 030209 endocrinology & metabolism lcsh:TX341-641 digestive system Coffee Article Food group Bile Acids and Salts 03 medical and health sciences Feces 0302 clinical medicine fluids and secretions fecal and serum bile acids Animals Humans Food science Vegans 030109 nutrition & dietetics Nutrition and Dietetics Chemistry Fishes Lipid metabolism Vegan Diet vegan diet Dietary pattern Middle Aged Margarine Reduced rank regression Diet Cross-Sectional Studies Omnivore dietary pattern reduced rank regression lcsh:Nutrition. Foods and food supply Food Science Transcription Factors |
Zdroj: | Nutrients Volume 12 Issue 1 Nutrients, Vol 12, Iss 1, p 47 (2019) |
ISSN: | 2072-6643 |
Popis: | Bile acids play an active role in fat metabolism and, in high-fat diets, elevated concentrations of fecal bile acids may be related to an increased risk of colorectal cancer. This study investigated concentrations of fecal and serum bile acids in 36 vegans and 36 omnivores. The reduced rank regression was used to identify dietary patterns associated with fecal bile acids. Dietary patterns were derived with secondary and conjugated fecal bile acids as response variables and 53 food groups as predictors. Vegans had higher fiber (p < 0.01) and lower fat (p = 0.0024) intake than omnivores. In serum, primary and glycine-conjugated bile acids were higher in vegans than in omnivores (p &le 0.01). All fecal bile acids were significantly lower in vegans compared to omnivores (p < 0.01). Processed meat, fried potatoes, fish, margarine, and coffee contributed most positively, whereas muesli most negatively to a dietary pattern that was directly associated with all fecal bile acids. According to the pattern, fat intake was positively and fiber intake was inversely correlated with bile acids. The findings contribute to the evidence that, in particular, animal products and fat may play a part in higher levels of fecal bile acids. |
Databáze: | OpenAIRE |
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