Side-Effects of Combined Radiation and Chemotherapy in the Treatment of Malignant Tumors
| Autor: | Charles R. Smart, Richard E. Ottoman, Donald B. Rochlin, Edward A. Langdon |
|---|---|
| Rok vydání: | 1963 |
| Předmět: |
medicine.medical_specialty
Chemotherapy Chlorambucil business.industry Mitomycin Incidence (epidemiology) medicine.medical_treatment Cancer Disease Toxicology medicine.disease Mitomycins Surgery Radiation therapy Fluorouracil Neoplasms Anticipation (genetics) Dactinomycin medicine Radiology Nuclear Medicine and imaging business medicine.drug |
| Zdroj: | Radiology. 81:1014-1017 |
| ISSN: | 1527-1315 0033-8419 |
| DOI: | 10.1148/81.6.1014 |
| Popis: | In a review of 99 cases of advanced solid tumors treated by a combination of irradiation and chemotherapy, it became apparent that toxic reactions capable of altering proposed treatment plans, even to requiring hospitalization, were frequent. Such reactions assume great importance in evaluating the response of any treatment technic. A high incidence of severe side-reactions, dangerous and debilitating to the patient, could well discourage therapy programs which produce only slightly better statistical improvement in the treatment of disease. In using therapeutic modalities in combination, the side-effects of each may become intensified. Great care must be taken not just in the treatment of these side-effects, but also in their anticipation. The patient must be questioned daily concerning minor symptoms in an effort to intercept and prevent the onset of major toxic reactions. In our series we have used predominantly 5-FU in combination with radiation. In a few cases, Actinomycin D, Mitomycin C, and chloram... |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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