Five years renal transplantation data: Single-center experience from Iraq
Autor: | Alaa H. Ali, Ali J Hashim Al-Saedi, Ali J M Al-Mudhaffer, Kais Hasan Abd Altaee |
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Jazyk: | angličtina |
Rok vydání: | 2016 |
Předmět: |
Nephrology
Adult Graft Rejection Male medicine.medical_specialty Time Factors Adolescent medicine.medical_treatment lcsh:Medicine Kaplan-Meier Estimate 030230 surgery Single Center Mycophenolic acid 03 medical and health sciences Young Adult 0302 clinical medicine Risk Factors Internal medicine medicine Living Donors Humans Child Survival rate Survival analysis Kidney transplantation Aged business.industry Graft Survival lcsh:R Immunosuppression General Medicine Middle Aged medicine.disease Kidney Transplantation Surgery Transplantation Treatment Outcome surgical procedures operative Iraq Kidney Failure Chronic 030211 gastroenterology & hepatology Drug Therapy Combination Female business Immunosuppressive Agents medicine.drug Program Evaluation |
Zdroj: | Saudi Journal of Kidney Diseases and Transplantation, Vol 27, Iss 2, Pp 341-347 (2016) |
ISSN: | 1319-2442 |
Popis: | Renal transplantation is the treatment of choice for patients with end-stage renal disease. In Iraq, renal transplantation started in 1973 and has continued until now with live donor transplantation, since deceased donor transplant program is not approved as yet. Long-term transplant data are still scarce. The aim of our study is to present data on transplantation and medical follow-up at one year and, survival analysis at one, three and five years. A total of 250 renal transplantations were performed at the Nephrology and Renal Transplantation Center, Baghdad between January 2009 and January 2014. It is a living donor, blood group compatible donor program. All patients received triple immunosuppression (calcineurine inhibitor, mycophenolate mofetil or mycophenolic acid, and steroid). The Kaplan-Meier method was used to determine the survival rate. There were 92 live related donors, 143 unrelated donors, and 15 spouse donors. The mean age was 34.07 ± 12.2 years. The one-year graft survival for related and unrelated donor transplants was 98.9% and 91.8%, respectively. Graft survival was lower (82.9%) in recipients with acute rejection episodes. The patient survival at one-year was 94%. The three-year graft and patient survival was 91% and 90%, respectively, and five-year survival for grafts and patients was 87.1% and 88%, respectively. The outcome of the renal transplantation in Iraq is improving. Long-term patient follow-up needs more meticulous attention. The development of renal transplant registry is critical for future planning. Moreover, renal transplantation practice in Iraq needs more social, religious, and governmental support. |
Databáze: | OpenAIRE |
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