Microhetero;geneity and polymorphism of human serum thryroxine-binding globulin. Study by isoelectric focusing and radioprint immunofixation
| Autor: | Yves Lasne, Odette Benzerara, Francoise Lasne |
|---|---|
| Rok vydání: | 1980 |
| Předmět: |
Immunofixation
Polymorphism Genetic Globulin biology Isoelectric focusing Chemistry Radioimmunoassay Biochemistry Genetics and Molecular Biology (miscellaneous) Molecular biology Thyroxine-Binding Proteins Sex hormone-binding globulin Serum thyroxine Isoelectric point biology.protein Humans Thyroxine-binding proteins Isoelectric Focusing |
| Zdroj: | Biochimica et biophysica acta. 624(2) |
| ISSN: | 0006-3002 |
| Popis: | A new technique of radioprint immunofixation following isoelectric focusing was applied to the study of microheterogeneity of thyroxine-binding globulin without purification, in individual sera; this protein appeared to give rise to at least seven bands with isoelectric points in the range of pI 4.2--5.0. Furthermore, two different distributions of the intensity of these bands were found in the sera investigated, suggesting the existence of thyroxine-binding globulin polymorphism in man. |
| Databáze: | OpenAIRE |
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