A case of β-catenin-positive hepatocellular adenoma with MR imaging sign of diffuse intratumoral fat deposition
| Autor: | Fukuo Kondo, Masaaki Akahane, Toru Takeshita, Junichi Fukushima, Keiji Sano, Mariko Gunji, Masaya Ishii, Toshio Fukusato, Junichi Kazaoka, Shigeru Furui, Toru Aoyama |
|---|---|
| Rok vydání: | 2015 |
| Předmět: |
Adult
Gadolinium DTPA Male medicine.medical_specialty Pathology Adenoma Urology Contrast Media Adenoma Liver Cell Benign tumor Malignant transformation Diagnosis Differential Internal medicine Humans Medicine Radiology Nuclear Medicine and imaging beta Catenin Incidental Findings Radiological and Ultrasound Technology medicine.diagnostic_test business.industry Liver Neoplasms Gastroenterology Magnetic resonance imaging General Medicine Hepatocellular adenoma Hepatology medicine.disease Magnetic Resonance Imaging Mr imaging Radiographic Image Enhancement Adipose Tissue Liver Catenin business |
| Zdroj: | Abdominal Imaging. 40:1487-1491 |
| ISSN: | 1432-0509 0942-8925 |
| DOI: | 10.1007/s00261-014-0342-3 |
| Popis: | Hepatocellular adenoma (HCA) is a rare primary benign tumor of the liver, which occurs predominantly in young and middle-aged women. Recently, the subclassification of HCA was proposed by the Bordeaux group. Subsequently, characteristic radiological and clinical features have been revealed in each HCA subtype. According to the previous literature, diffuse intratumoral fat deposition is a very common finding in hepatocyte nuclear factor 1α-negative HCA, but this finding has been reported in β-catenin-positive HCA in the literature for only one case. In this case report, we report the second case of β-catenin-positive HCA with MR imaging sign of diffuse intratumoral fat deposition, confirmed immunohistologically on the basis of a surgical specimen. In addition, our case showed hypovascularity and isointensity on the hepatobiliary phase which have been reported as characteristic findings in β-catenin-positive HCA. Diffuse intratumoral fat deposition can be observed in β-catenin-positive HCA, which has a greater probability of malignant transformation than other types of HCA. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full text from SpringerLink