Differences in Speed of Response of Depressive Symptom Dimensions in Older Persons during Electroconvulsive Therapy

Autor: Eric van Exel, Roos C. van der Mast, Annemiek Dols, Max L. Stek, Pascal Sienaert, E.M. Veltman, Jos W. R. Twisk, Sophie van Hulten, Filip Bouckaert, Didi Rhebergen
Přispěvatelé: Epidemiology and Data Science, Neurology, Psychiatry, Amsterdam Neuroscience - Mood, Anxiety, Psychosis, Stress & Sleep, APH - Mental Health, APH - Aging & Later Life, ACS - Atherosclerosis & ischemic syndromes, Methodology and Applied Biostatistics
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Male
medicine.medical_treatment
Neuroscience (miscellaneous)
factor analysis
late life depression
Affect (psychology)
behavioral disciplines and activities
Suicidal Ideation
Cohort Studies
course trajectories
03 medical and health sciences
0302 clinical medicine
Electroconvulsive therapy
SDG 3 - Good Health and Well-being
mental disorders
Reaction Time
Psychology
Medicine
Humans
Electroconvulsive Therapy
Biology
Suicidal ideation
Depression (differential diagnoses)
Depressive symptoms
Aged
Aged
80 and over
Psychiatric Status Rating Scales
Depressive Disorder
Major
major depressive disorder
business.industry
Depression
Late life depression
Middle Aged
medicine.disease
030227 psychiatry
Psychiatry and Mental health
Affect
Treatment Outcome
Major depressive disorder
Female
Human medicine
medicine.symptom
business
030217 neurology & neurosurgery
Cohort study
Clinical psychology
Zdroj: Veltman, E M, Van Hulten, S, Twisk, J, Dols, A, Van Exel, E, Stek, M L, Sienaert, P, Bouckaert, F, Van Der Mast, R C & Rhebergen, D 2019, ' Differences in Speed of Response of Depressive Symptom Dimensions in Older Persons during Electroconvulsive Therapy ', Journal of ect, vol. 35, no. 1, pp. 35-39 . https://doi.org/10.1097/YCT.0000000000000506
The journal of ECT, 35(1), 35-39
Journal of ECT, 35(1), 35-39. LIPPINCOTT WILLIAMS & WILKINS
Journal of ect, 35(1), 35-39. Lippincott Williams and Wilkins
Veltman, E M, van Hulten, S, Twisk, J, Dols, A, van Exel, E, Stek, M L, Sienaert, P, Bouckaert, F, van der Mast, R C & Rhebergen, D 2019, ' Differences in Speed of Response of Depressive Symptom Dimensions in Older Persons During Electroconvulsive Therapy ', The journal of ECT, vol. 35, no. 1, pp. 35-39 . https://doi.org/10.1097/YCT.0000000000000506
Journal of ECT
ISSN: 1533-4112
1095-0680
Popis: Introduction Electroconvulsive therapy (ECT) is an important and effective treatment for depression. However, research on course trajectories of depressive symptoms during ECT is limited. Insight into putative differences in speed of response of depressive symptom dimensions may enable clinicians to optimally inform patients and their relatives. Therefore, we aim to examine course trajectories of depressive symptom dimensions in depressed older persons during ECT.Methods Data were derived from the Mood Disorders in Elderly treated with Electro Convulsive Therapy study, including 110 persons, aged 55 years or more, with a current diagnosis of major depressive disorder and referred for ECT. Exploratory factor analysis was used to identify symptom dimensions, using the 10 depression items of the Montgomery-Åsberg Depression Rating Scale (MADRS). Differences in course trajectories of symptom dimension during 2 weeks were examined by multilevel analyses.Results Three symptom dimensions were identified: a “mood,” “melancholic,” and “suicidal” dimension. Mood showed a significantly greater severity decline as compared with melancholic and suicidal at the 1-week follow-up. At the 2-week follow-up, both mood and melancholic demonstrated a significantly greater decline as compared with suicidal. However, because scores on the suicidality item of the Montgomery-Asberg Depression Rating Scale were already lower at baseline compared with the other items, a floor effect cannot be ruled out.Discussion All symptom dimensions of depression showed a rapid response to ECT. Our findings did not support the general assumption that suicidal symptoms may be the first to improve. However, a floor effect on the suicidality item cannot be ruled out.
Databáze: OpenAIRE
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