An update on VEXAS syndrome
| Autor: | Adam Al-Hakim, Sinisa Savic |
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| Rok vydání: | 2022 |
| Předmět: | |
| Zdroj: | Expert review of clinical immunology. |
| ISSN: | 1744-8409 |
| Popis: | VEXAS (vacuoles, E1 enzyme, X-linked, autoinflammatory, somatic) syndrome is a recently described, late-onset, acquired autoinflammatory disorder caused by mutations in theThis review describes the discovery of VEXAS, relevant genetic causes and immunopathology of the disease. A detailed account of its various clinical manifestations and disease mimics is provided. Current treatment and management options are discussed.New rare variants in |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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