Analysis of Post-Colonoscopy Colorectal Cancer and Its Subtypes in a Screening Programme

Autor: María José Fernández-Landa, Isabel Portillo, Luis Bujanda, Isabel Idigoras-Rubio, Saloa Unanue-Arza, Isabel Bilbao-Iturribarria
Rok vydání: 2021
Předmět:
Zdroj: Addi. Archivo Digital para la Docencia y la Investigación
instname
Universidad de Cantabria (UC)
Cancers, Vol 13, Iss 5105, p 5105 (2021)
Cancers
Volume 13
Issue 20
ISSN: 2072-6694
DOI: 10.3390/cancers13205105
Popis: Using the algorithm of the World Endoscopy Organisation (WEO), we have studied retrospectively all colorectal cancers, both detected and non-detected by the Basque Country screening programme from 2009 to 2017. In the screening programme 61,335 colonoscopies were performed following a positive Faecal Immunochemical test (FIT) (≥20 µg Hb/g faeces) and the 128 cases of post-colonoscopy colorectal cancer (PCCRC) detected were analysed. Among them, 50 interval type PCCRCs were diagnosed (before the recommended surveillance), 0.8 cases per 1000 colonoscopies performed, and 78 non-interval type PCCRCs (in the surveillance carried out at the recommended time or delayed), 1.3 per 1000 colonoscopies. Among the non-interval type PCCRCs, 61 cases were detected in the surveillance carried out at the recommended time (type A) and 17 when the surveillance was delayed (type B), 1 case per 1000 colonoscopies performed and 0.28 cases per 1000 colonoscopies performed, respectively. Interval type PCCRC is less frequent than non-interval type PCCRC. In interval type PCCRCs, CRCs detected in advanced stages (stages III–IV) were significantly more frequent than those detected in early stages, compared to those of non-interval type PCCRCs (OR = 3.057
95% CI, 1.410–6.625
p <
0.005). Non-interval type B PCCRCs are less frequent than non-interval type A PCCRCs, but the frequency of advanced stages is higher in interval type B PCCRCs.
Databáze: OpenAIRE
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