The effectiveness of antimicrobial photodynamic therapy with prodigiosin against reference strains of Staphylococcus aureus, Escherichia coli, and Pseudomonas aeruginosa

Autor:	Amin Derakhshanfar, Banafsheh Rastegari, Hossein Sharifi, Hossein Khajeh-Zadeh, Javad Moayedi
Rok vydání:	2022
Předmět:	Staphylococcus aureus Photochemotherapy Anti-Infective Agents Bacteria Prodigiosin Pseudomonas aeruginosa Escherichia coli Humans Surgery Dermatology Staphylococcal Infections Anti-Bacterial Agents
Zdroj:	Lasers in medical science. 37(9)
ISSN:	1435-604X
Popis:	Prodigiosin (PG) is a secondary metabolite of bacterial origin that is able to absorb the visible light and plays a role as a photosensitizer in photodynamic therapy (PDT). This in vitro study aimed to investigate the cytotoxicity of PG-mediated PDT against the reference strains of Staphylococcus aureus (S. aureus), Escherichia coli (E. coli), and Pseudomonas aeruginosa (P. aeruginosa). The minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) of PG were determined. Each strain was then allocated into four groups as follows: G1: control (no treatment), G2: PG-treated groups that received different PG concentrations (1000-1.95 μM), G3: laser-treated group (wavelength: 520 nm, radiation dose: 187 J/cm
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c27462fab7950fea220a147be9a47fb2 https://pubmed.ncbi.nlm.nih.gov/36156750 Zobrazit plný text záznamu Full text from SpringerLink