Associations of HIV and iron status with gut microbiota composition, gut inflammation and gut integrity in South African school-age children: a two-way factorial case-control study

Autor: Charlene Goosen, Sebastian Proost, Jeannine Baumgartner, Kashish Mallick, Raul Y. Tito, Shaun L. Barnabas, Mark F. Cotton, Michael B. Zimmermann, Jeroen Raes, Renée Blaauw
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Journal of Human Nutrition and Dietetics, 36 (3)
ISSN: 0952-3871
1365-277X
Popis: BackgroundHuman immunodeficiency virus (HIV) and iron deficiency (ID) affect many African children. Both HIV and iron status interact with gut microbiota composition and related biomarkers. The study's aim was to determine the associations of HIV and iron status with gut microbiota composition, gut inflammation and gut integrity in South African school-age children.MethodsIn this two-way factorial case-control study, 8- to 13-year-old children were enrolled into four groups based on their HIV and iron status: (1) With HIV (HIV+) and ID (n = 43), (2) HIV+ and iron-sufficient nonanaemic (n = 41), (3) without HIV (HIV-) and ID (n = 44) and (4) HIV- and iron-sufficient nonanaemic (n = 38). HIV+ children were virally suppressed (
Journal of Human Nutrition and Dietetics, 36 (3)
ISSN:0952-3871
ISSN:1365-277X
Databáze: OpenAIRE
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