Voltammetric Determination of Sulfaclozine Sodium at Sephadex-modified Carbon Paste Electrode
| Autor: | Afaf Abou El Khair, Hanaa Saleh, Magda El Henawee, Neven Ahmed, Emad M. Hussien |
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| Rok vydání: | 2020 |
| Předmět: |
Horizontal scan rate
Calibration curve Sodium chemistry.chemical_element square wave voltammetry Electrochemistry lcsh:Chemistry lcsh:QD1-999 chemistry Sephadex Electrode sulfaclozine sodium General Earth and Planetary Sciences sephadex carbon past electrode Cyclic voltammetry Carbon General Environmental Science Nuclear chemistry |
| Zdroj: | Acta Chimica Slovenica, Vol 67, Iss 3, Pp 757-763 (2020) |
| ISSN: | 1580-3155 |
| Popis: | The electrochemical behavior of Sulfaclozine Sodium (SLC) was studied at a bare and sephadex-modified carbon paste electrodes by cyclic voltammetry and square wave voltammetry. The cyclic voltammetry (CV) showed a well-defined irreversible oxidation peak at 0.94 V in Britton- Robinson buffer pH 7.0. The strong affinity of SLC to sephadex allowed accumulation of SLC at the surface of electrode and thus higher electrochemical sensitivity to SLC. The influence of sephadex loading, the pH of the solution and the scan rate on the peak current was studied. A linear calibration curve covering the concentration range from 0.005 to 1 mM was obtained using SWV. The method was successfully applied for the determination of SLC in the veterinary pharmaceutical formulations with satisfactory accuracy and precision. |
| Databáze: | OpenAIRE |
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