Degradation of cytosolic ribosomes by autophagy-related pathways
| Autor: | Diane C. Bassham, Gustavo C. MacIntosh |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
0301 basic medicine
Autophagy Arabidopsis Cellular homeostasis Plant Science General Medicine Vacuole Biology Ribosomal RNA biology.organism_classification Ribosome Cell biology 03 medical and health sciences Cytosol 030104 developmental biology Eukaryotic organism RNA Ribosomal Genetics Ribosomes Agronomy and Crop Science |
| Zdroj: | Plant Science. 262:169-174 |
| ISSN: | 0168-9452 |
| DOI: | 10.1016/j.plantsci.2017.05.008 |
| Popis: | Ribosomes are essential molecular machines that require a large cellular investment, yet the mechanisms of their turnover are not well understood in any eukaryotic organism. Recent advances in Arabidopsis suggest that plants utilize selective mechanisms to transport rRNA or ribosomes to the vacuole, where rRNA is degraded and the breakdown products recycled to maintain cellular homeostasis. This review focuses on known mechanisms of rRNA turnover and explores unanswered questions on the specificity and pathways of ribosome turnover and the role of this process in maintenance of cellular homeostasis. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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