Modulation of sheep erythrocyte receptor expression by anti-CD4, anti-CD8, and anti-HLA antibodies
| Autor: | J. A. Nogueira-Machado, M. M. Chaves, D. N. Silva-Teixeira |
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| Rok vydání: | 1988 |
| Předmět: |
Antigens
Differentiation T-Lymphocyte Erythrocytes Rosette Formation biology medicine.drug_class Immunology Receptors Antigen T-Cell General Medicine Monoclonal antibody Molecular biology Peripheral blood mononuclear cell Antibodies chemistry.chemical_compound Red blood cell medicine.anatomical_structure chemistry Cell surface receptor HLA Antigens biology.protein medicine Antibody Receptor Cyclic guanosine monophosphate CD8 |
| Zdroj: | Scandinavian journal of immunology. 27(2) |
| ISSN: | 0300-9475 |
| Popis: | The modulation of E receptors on T cells by anti-CD4 and/or anti-CD8 is reported. The percentage of E rosette-forming cells (RFC) was decreased when sheep erythrocyte and mononuclear cells were incubated in the presence of monoclonal antibodies anti-CD4 and/or anti-CD8. This inhibition was not due to shedding of the E receptor and it was reversed by 8-Br.-3',5' cyclic guanosine monophosphate (cGMP). In contrast, anti-HLA antibodies induced an enhancement of sheep erythrocyte receptor expression evaluated by RFC. |
| Databáze: | OpenAIRE |
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