Reproducibility and validity of ultrasound for the measurement of visceral and subcutaneous adipose tissues
| Autor: | Inga Schlecht, J. Freese, Beate Fischer, Christian Stroszczynski, Philipp Wiggermann, Ute Nöthlings, Michael F. Leitzmann, Diana Rubin, Manja Koch, Gundula Behrens |
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| Rok vydání: | 2014 |
| Předmět: |
Adult
Male medicine.medical_specialty Pathology Separate sample Endocrinology Diabetes and Metabolism Subcutaneous Fat Adipose tissue Intra-Abdominal Fat Young Adult Endocrinology Internal medicine Ultrasound method medicine Abdominal fat Humans Aged Ultrasonography Observer Variation Reproducibility medicine.diagnostic_test business.industry Ultrasound Reproducibility of Results Magnetic resonance imaging Middle Aged Magnetic Resonance Imaging Adipose Tissue Feasibility Studies Female Subcutaneous adipose tissue Nuclear medicine business |
| Zdroj: | Metabolism. 63:1512-1519 |
| ISSN: | 0026-0495 |
| Popis: | Background Ultrasound represents a low-cost and widely available field method for assessing visceral adipose tissue (VAT) and subcutaneous adipose tissue (SAT) but its measurement properties are uncertain. The aim of the current study was to examine the reproducibility and validity of ultrasound to quantify abdominal fat compartments. Methods In two study centers, VAT and SAT thicknesses were quantified by ultrasound two times by two observers each among 127 adults aged 20–70 years. In a separate sample of 30 adults, the ultrasound method was validated by comparing VAT and SAT thicknesses with VAT and SAT areas at vertebrae L2/L3 as obtained by a single magnetic resonance imaging (MRI) slice. Results For VAT, the intra-rater reproducibility values for observers 1 and 2 were r = 0.996 (95% CI = 0.994–0.997) and r = 0.999 (95% CI = 0.999–0.999), respectively. For SAT, the intra-rater reproducibility values were r = 0.992 (95% CI = 0.989–0.994) and r = 0.993 (95% CI = 0.990–0.995), respectively. The inter-rater reproducibility values for VAT and SAT were r = 0.998 (95% CI = 0.997–0.999) and r = 0.990 (95% CI = 0.986–0.993), respectively. For VAT and SAT, the correlation coefficients between ultrasound and MRI measurements were r = 0.898 ( P P Conclusion Ultrasound provides reproducible and valid estimates of VAT and SAT and represents a useful method to assess abdominal fat in large scale epidemiologic studies. |
| Databáze: | OpenAIRE |
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