Effect of advanced brain atrophy and vitamin deficiency on cognitive functions in non-demented subjects
| Autor: | H. Frey, Pekka Laippala, J. Salo, T. Pirttilä |
|---|---|
| Rok vydání: | 2009 |
| Předmět: |
Male
Vitamin Neurocognitive Disorders Physiology Neuropsychological Tests Cerebral Ventricles chemistry.chemical_compound Atrophy Vitamin deficiency Reference Values Cognitive Changes medicine Humans Cognitive skill skin and connective tissue diseases Aged Brain Vitamin B 12 Deficiency Cognition General Medicine Middle Aged medicine.disease Control subjects Neurology chemistry Ageing Mental Recall Dementia Female sense organs Neurology (clinical) Cognition Disorders Tomography X-Ray Computed Psychology Neuroscience |
| Zdroj: | Acta Neurologica Scandinavica. 87:161-166 |
| ISSN: | 1600-0404 0001-6314 |
| DOI: | 10.1111/j.1600-0404.1993.tb04094.x |
| Popis: | The relationship between the cognitive functions, structural changes of the brain and vitamin levels was evaluated in 36 non-demented subjects with advanced brain atrophy, and 57 age- and sex-matched healthy controls. In the control subjects ageing was associated with mild decline of cognitive skills, but the cognitive changes were not linked to the structural changes of the brain. In contrast, advanced brain atrophy and vitamin deficiency was related to the decline of complex cognitive functions in the atrophy group. Our results indicate that there are limits of normal age-related changes of the brain structure, and advanced brain atrophy on CT scans increase the probability of mild deficits of the cognitive skills. |
| Databáze: | OpenAIRE |
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