Scavenger effect of a mango (Mangifera indica L.) food supplement’s active ingredient on free radicals produced by human polymorphonuclear cells and hypoxanthine–xanthine oxidase chemiluminescence systems

Autor:	René Delgado, Alberto J. Núñez-Sellés, Gabino Garrido, Deyarina Gonzalez, Cheyla Romay
Rok vydání:	2008
Předmět:	chemistry.chemical_classification Reactive oxygen species Oxidase test Antioxidant Superoxide medicine.medical_treatment General Medicine Analytical Chemistry chemistry.chemical_compound Biochemistry chemistry medicine Mangifera Mangiferin Xanthine oxidase Hypoxanthine Food Science
Zdroj:	Food Chemistry. 107:1008-1014
ISSN:	0308-8146
Popis:	The in vitro antioxidant and free radical scavenging properties of a stem bark aqueous extract of mango tree ( Mangifera indica L.), whose formulations are used in Cuba as food supplements under the brand name of Vimang ® , were studied. Luminol-enhanced chemiluminescence was used to elucidate the effect of this extract on the generation of reactive oxygen species in PMA- or zymosan-stimulated human polymorphonuclear leukocytes and on superoxide radicals generated in the hypoxanthine–xanthine oxidase reaction. Chemiluminescence was reduced in a dose-dependent manner at extract concentrations from 5 to 100 μg/ml, most probably by inhibiting the superoxide generation reaction. Part of this M. indica extract antioxidant activity could be ascribed to the presence of mangiferin as its main component.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c24e538934da10d742dc66bb6694b17f https://doi.org/10.1016/j.foodchem.2007.09.012 Zobrazit plný text záznamu Full Text from ScienceDirect