Updated standard operating procedures for electrochemotherapy of cutaneous tumours and skin metastases
Autor: | Marco Benazzo, Victor Farricha, J. Odili, Lluis M. Mir, Pietro Curatolo, A. James P. Clover, Luca Giovanni Campana, Declan M. Soden, Antonio Occhini, Tobian Muir, Christian Kunte, Karin Dahlstrøm, Pietro Quaglino, Julie Gehl, Louise Wichmann Matthiessen, Giulia Bertino, Gregor Sersa |
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Přispěvatelé: | Laboratory of the Department of Oncology (DEPARTMENT OF ONCOLOGY), Herlev and Gentofte Hospital, Institute of Oncology - Ljubljana, Institute of Oncology Ljubljana, Cork Cancer Reasearch Centre, Cork Cancer Reasearch, Institut Gustave Roussy (IGR) |
Rok vydání: | 2018 |
Předmět: |
0301 basic medicine
Electrochemotherapy medicine.medical_specialty Consensus Skin Neoplasms [SDV]Life Sciences [q-bio] Operating procedures [SDV.CAN]Life Sciences [q-bio]/Cancer 03 medical and health sciences 0302 clinical medicine Breast cancer Skin tumours Nuclear Medicine and Imaging medicine Humans Radiology Nuclear Medicine and imaging Melanoma ComputingMilieux_MISCELLANEOUS business.industry Reference Standards Practice Guidelines as Topic Hematology Oncology Radiology Nuclear Medicine and Imaging General Medicine medicine.disease 3. Good health Plastic surgery 030104 developmental biology 030220 oncology & carcinogenesis Head and neck surgery [SDV.IB]Life Sciences [q-bio]/Bioengineering Radiology Skin cancer business [SDV.MHEP]Life Sciences [q-bio]/Human health and pathology |
Zdroj: | Acta Oncologica Acta Oncologica, Taylor & Francis, 2018, 57 (7), pp.874-882. ⟨10.1080/0284186X.2018.1454602⟩ |
ISSN: | 1651-226X 0284-186X |
Popis: | Electrochemotherapy is now in routine clinical use to treat cutaneous metastases of any histology, and is listed in national and international guidelines for cutaneous metastases and primary skin cancer. Electrochemotherapy is used by dermatologists, surgeons, and oncologists, and for different degrees and manifestations of metastases to skin and primary skin tumours not amenable to surgery. This treatment utilises electric pulses to permeabilize cell membranes in tumours, thus allowing a dramatic increase of the cytotoxicity of anti-cancer agents. Response rates, often after only one treatment, are very high across all tumour types. The most frequent indications are cutaneous metastases from malignant melanoma and breast cancer. In 2006, standard operating procedures (SOPs) were written for this novel technology, greatly facilitating introduction and dissemination of the therapy. Since then considerable experience has been obtained treating a wider range of tumour histologies and increasing size of tumours which was not originally thought possible. A pan-European expert panel drawn from a range of disciplines from dermatology, general surgery, head and neck surgery, plastic surgery, and oncology met to form a consensus opinion to update the SOPs based on the experience obtained. This paper contains these updated recommendations for indications for electrochemotherapy, pre-treatment information and evaluation, treatment choices, as well as follow-up. |
Databáze: | OpenAIRE |
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