Hepatitis E virus infection and waste pickers: A case-control seroprevalence study
| Autor: | Eda Guadalupe Ramírez-Valles, Verónica Dayali Gutierrez-Martinez, Antonio Sifuentes-Alvarez, Cosme Alvarado-Esquivel |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
Adult
Male medicine.medical_specialty Adolescent Population Waste picker medicine.disease_cause Logistic regression 03 medical and health sciences Young Adult 0302 clinical medicine McNemar's test Hepatitis E virus Risk Factors Seroepidemiologic Studies Virology Environmental health Epidemiology medicine Odds Ratio Seroprevalence Humans Recycling 030212 general & internal medicine Hepatitis Antibodies education Aged education.field_of_study business.industry Case-control study virus diseases Middle Aged digestive system diseases Hepatitis E Refuse Disposal Occupational Diseases Infectious Diseases Case-Control Studies Immunoglobulin G Workforce 030211 gastroenterology & hepatology Female business |
| Zdroj: | Journal of medical virologyREFERENCES. 93(6) |
| ISSN: | 1096-9071 |
| Popis: | Whether waste pickers are a risk group for hepatitis E virus (HEV) infection is largely unknown. This study aimed to determine the association between HEV exposure and the occupation of waste picker and the work characteristics of waste pickers. An age-and gender-matched case-control seroprevalence study of 86 waste pickers and 86 control subjects of the general population was performed. We determined anti-HEV IgG antibodies in sera of cases and controls using a commercially available enzyme-linked immunoassay. The McNemar's test was used to assess the association between HEV seropositivity and the occupation of waste picker. The association between HEV seropositivity and work characteristics of waste pickers was assessed by bivariate and logistic regression analyses. Anti-HEV IgG antibodies were detected in 14 (16.3%) of the 86 waste pickers and in 8 (9.3%) of the 86 control subjects (McNemar's pair test: OR = 13.0; 95% CI: 0.73-230.77; P=0.02). Bivariate analysis showed that HEV exposure was associated with an ill status (P=0.01) and reflexes impairment (P=0.009). Logistic regression analysis showed that HEV seropositivity was associated with increasing age (OR = 6.52; 95% CI: 1.95-21.78; P=0.002) and raising pigs (OR = 12.01; 95% CI: 1.48-97.26; P=0.02). This is the first age- and gender-matched case-control study on the association between HEV infection and the occupation of waste picker. Waste pickers represent a risk group for HEV infection. Factors associated with HEV seropositivity found in this study may help in the design of optimal planning to avoid HEV infection. This article is protected by copyright. All rights reserved. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Plný text