Blood oxypurines and erythrocyte 2, 3-diphosphoglycerate levels at high altitude hypoxia
| Autor: | Genyo Mitarai, Shizuo Mori, Yoshinao Katsumata, Ryoichi Hayashi, Masataka Yoshino |
|---|---|
| Rok vydání: | 1980 |
| Předmět: |
Adult
Male medicine.medical_specialty Erythrocytes Purinones Chemistry Altitude General Medicine High altitude hypoxia Diphosphoglyceric Acids General Biochemistry Genetics and Molecular Biology Mice Oxygen Consumption Simulated altitude Endocrinology Internal medicine medicine Animals Humans Tissue hypoxia General Pharmacology Toxicology and Pharmaceutics Diphosphoglycerate Hypoxia Oxygen pressure |
| Zdroj: | Life Sciences. 27:1265-1269 |
| ISSN: | 0024-3205 |
| DOI: | 10.1016/0024-3205(80)90219-2 |
| Popis: | Effect of acute high altitude hypoxia on the levels of plasma oxypurines and erythrocyte 2, 3-diphosphoglycerate (2, 3-DPG) was investigated. Exposure to simulated altitude at 4000, 5000, and 6000 m rapidly increased plasma oxypurines as well as erythrocyte 2, 3-DPG in human and mice. A close correlation of the concentration of oxypurines and 2, 3-DPG in human with the oxygen pressure, suggesting that the levels of these metabolites may be indicative of tissue hypoxia. |
| Databáze: | OpenAIRE |
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