Disease-related and overall survival in dogs with cranial cruciate ligament disease, a historical cohort study
| Autor: | Annika Bergström, Gudrun Seeberg Boge, Karolina Engdahl, Elena Regine Moldal, Odd V. Höglund, Jeanette Hanson, Eystein Skjerve, Randi I. Krontveit, Ulf Emanuelson |
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| Rok vydání: | 2020 |
| Předmět: |
Male
medicine.medical_specialty 040301 veterinary sciences medicine.medical_treatment 030231 tropical medicine Disease Osteotomy Cohort Studies 0403 veterinary science Cruciate ligament Hospitals Animal 03 medical and health sciences Dogs 0302 clinical medicine Food Animals medicine Overall survival Animals Dog Diseases Anterior Cruciate Ligament Retrospective Studies Sweden Norway business.industry Proportional hazards model Anterior Cruciate Ligament Injuries Medical record 04 agricultural and veterinary sciences Clinical Science medicine.disease Comorbidity Surgery medicine.anatomical_structure Female Animal Science and Zoology business Historical Cohort |
| Zdroj: | Preventive Veterinary Medicine |
| ISSN: | 0167-5877 |
| Popis: | Objective To analyse the effect of treatment method and other risk factors on survival in dogs with cranial cruciate ligament disease (CCLD). Methods A historical cohort study of 333 dogs presenting with CCLD at two University Hospitals (2011–2016) was performed. Signalment, history, treatment and follow-up details were retrieved from medical records, dog owners and referring veterinarians. Treatment groups were defined; conservative or surgical with either lateral fabellotibial suture (LFS) or osteotomy procedures. Multivariable Cox proportional hazards models were applied to evaluate risk factors for disease-related and overall survival. Results Sixty-five dogs were conservatively managed, 125 treated with LFS and 143 with osteotomy techniques. At follow-up (autumn 2018), 164 dogs (49.3 %) were alive and 169 (50.7 %) were dead. Both final Cox proportional hazards models included variables for treatment, age, weight and hospital. In addition, the final disease-related model included a variable for orthopaedic comorbidity, while non-orthopaedic comorbidities and a time-varying effect for age on a linear scale were included in the overall survival model. Treatment method was found to have an effect on both disease-related and overall survival and surgical treatment was associated with a lower hazard than conservative treatment. Conclusion Survival in dogs with CCLD is influenced by treatment strategy, comorbidities, age and weight. |
| Databáze: | OpenAIRE |
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