Stress myocardial perfusion with qualitative magnetic resonance and quantitative dynamic computed tomography: comparison of diagnostic performance and incremental value over coronary computed tomography angiography
| Autor: | Andrew Wragg, Francesca Pugliese, Magnus T. Jensen, Mark Westwood, Bunny Saberwal, Martina C. de Knegt, Ruhaid Khurram, Alexia Rossi, Anthony Mathur, Steffen E. Petersen, Koen Nieman, Fabian Bamberg |
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| Rok vydání: | 2020 |
| Předmět: |
medicine.diagnostic_test
business.industry Magnetic resonance imaging Perfusion scanning General Medicine Fractional flow reserve Blood flow 030204 cardiovascular system & hematology medicine.disease 030218 nuclear medicine & medical imaging Coronary artery disease 03 medical and health sciences Myocardial perfusion imaging Stenosis 0302 clinical medicine medicine Radiology Nuclear Medicine and imaging Cardiology and Cardiovascular Medicine Nuclear medicine business Perfusion |
| Zdroj: | European heart journal. Cardiovascular Imaging. |
| ISSN: | 2047-2412 |
| Popis: | Aims Assessment of haemodynamically significant coronary artery disease (CAD) using cardiovascular magnetic resonance (CMR) imaging perfusion or dynamic stress myocardial perfusion imaging by computed tomography (CT perfusion) may aid patient selection for invasive coronary angiography (ICA). We evaluated the diagnostic performance and incremental value of qualitative CMR perfusion and quantitative CT perfusion complementary to cardiac computed tomography angiography (CCTA) for the diagnosis of haemodynamically significant CAD using fractional flow reserve (FFR) and quantitative coronary angiography (QCA) as reference standard. Methods and results CCTA, qualitative visual CMR perfusion, visual CT perfusion, and quantitative relative myocardial blood flow (CT-MBF) were performed in patients with stable angina pectoris. FFR was measured in coronary vessels with stenosis visually estimated between 30% and 90% diameter reduction on ICA. Haemodynamically significant CAD was defined as FFR Conclusion Visual CMR perfusion and relative CT-MBF outperformed visual CT perfusion and provided incremental discrimination compared with CCTA alone for the diagnosis of haemodynamically significant CAD. |
| Databáze: | OpenAIRE |
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