Immunohistochemical evaluation of the inflammatory response in periodontal disease
| Autor: | Ruthinéia Diógenes Alves Uchôa Lins, Cláudia Roberta Leite Vieira Figueiredo, Lélia Maria Guedes Queiroz, Ericka Janine Dantas da Silveira, Gustavo Pina Godoy, Roseana de Almeida Freitas |
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| Jazyk: | angličtina |
| Rok vydání: | 2008 |
| Předmět: |
CD4-Positive T-Lymphocytes
Pathology medicine.medical_specialty Lymphocyte Connective tissue Antigens Differentiation Myelomonocytic Cell Count Lymphocyte Activation Epithelium Immunophenotyping chronic gingivitis Antigen Antigens CD Medicine Humans IL-2 receptor Lymphocyte Count General Dentistry Cell Shape CD20 Lamina propria B-Lymphocytes immunological response Mucous Membrane biology business.industry CD68 Macrophages S100 Proteins Interleukin-2 Receptor alpha Subunit chronic periodontitis Dendritic Cells Macrophage Activation Antigens CD20 Gingivitis Immunohistochemistry medicine.anatomical_structure Connective Tissue immunohistochemical CD4 Antigens Chronic Disease Chronic Periodontitis biology.protein Leukocytes Mononuclear business |
| Zdroj: | Brazilian Dental Journal, Volume: 19, Issue: 1, Pages: 14-9, Published: 2008 Brazilian Dental Journal v.19 n.1 2008 Brazilian Dental Journal Fundação Odontológica de Ribeirão Preto (FUNORP) instacron:FUNORP |
| Popis: | In order to contribute to the knowledge of the pathogenesis of periodontal disease, an immunohistochemical analysis of the density of inflammatory mononucleated cells and the number of dendritic cells was performed using anti-CD4, anti-CD20, anti-CD25, anti-CD68 and anti-protein S-100 antibodies in 17 cases of chronic gingivitis (CG) and 25 of chronic periodontitis (CP). The CD4+ and CD68+ cells exhibited a diffuse distribution in the connective tissue. CD20+ cell distribution was predominantly in groups and the CD25+ cells exhibited a diffuse or focal distribution. The S-100+ cells were identified in the epithelium and the lamina propria, exhibiting distinct morphology and number. The statistical analysis showed no significant differences (p>0.05) between CG and CP regarding the density of the CD4+ and CD20+ cells and the number of S-100+ cells. However, significant differences (p |
| Databáze: | OpenAIRE |
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