Biological disease-modifying antirheumatic drugs in juvenile idiopathic arthritis of polyarticular course, enthesitis-related arthritis, and psoriatic arthritis: a consensus statement
| Autor: | Sik Nin Wong, Lettie Ck Leung, Roanna Hm Yeung, Kwok-Wai Lee, Sy Kong, Niko Kc Tse, Patrick Cy Chong, Assunta Ch Ho, Winnie Ky Chan |
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| Rok vydání: | 2020 |
| Předmět: |
Biological Products
medicine.medical_specialty Consensus business.industry Inflammatory arthritis Arthritis Psoriatic MEDLINE Arthritis Disease Guideline medicine.disease Arthritis Juvenile Clinical trial Psoriatic arthritis Antirheumatic Agents Family medicine Practice Guidelines as Topic medicine Humans Child Antirheumatic drugs business Randomized Controlled Trials as Topic |
| Zdroj: | Hong Kong Medical Journal. 26:56-65 |
| Popis: | Objectives Juvenile idiopathic arthritis (JIA) is the most common type of inflammatory arthritis in children. Treatment options have been expanded since the introduction of biologics, which are highly effective. The existing local JIA treatment guideline was published more than a decade ago, when use of biologics was not as common. In this article, we review the latest evidence on using biologics in three JIA subtypes: JIA of polyarticular course (pcJIA), enthesitis-related arthritis (ERA), and psoriatic arthritis (PsA). Based on the latest information, an update on eligibility, response assessment, termination, and safety information for using biologics in these patients was performed. Consensus process The JIA Work Group, which consisted of nine paediatricians experienced in managing JIA, was convened in 2016. Publications before July 2017 were screened. Eligible articles were clinical trials, extension studies, systemic reviews, and recommendations from international societies and regulatory agencies about the use of biologics in pcJIA, ERA, and PsA. Evidence extraction, appraisal, and drafting of propositions were performed by two reviewers. Extracted evidence and drafted propositions were presented and discussed at the first two meetings. Overwhelming consensus was obtained at the final meeting in May 2018. Seven practice consensus statements were formulated. Regular review should be performed to keep the practice evidence-based and up-to-date. |
| Databáze: | OpenAIRE |
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