Entomological Assessment of Onchocerca Species Transmission by Black Flies in Selected Communities in the West Region of Cameroon
| Autor: | Rose Njemini, Joseph Kamga, Cabirou Mounchili Shintouo, Stephen Mbigha Ghogomu, Jacob Souopgui, Joel Ebai Nguve, Robert Adamu Shey, Fru Bertha Asa |
|---|---|
| Přispěvatelé: | Faculty of Medicine and Pharmacy, Gerontology, Research in Geriatrics and Gerontology, Frailty in Ageing |
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
0301 basic medicine
Microbiology (medical) Veterinary medicine Elimination 030231 tropical medicine lcsh:Medicine Biology Onchocerciasis Article law.invention ivermectin 03 medical and health sciences 0302 clinical medicine Ivermectin elimination law parasitic diseases medicine Immunology and Allergy Mass treatment O-150 PCR Parasite transmission Molecular Biology Medicine(all) General Immunology and Microbiology poolscreen lcsh:R onchocerciasis Généralités medicine.disease 030104 developmental biology Infectious Diseases Transmission (mechanics) Poolscreen Geriatrics and Gerontology Onchocerca species medicine.drug |
| Zdroj: | Pathogens Pathogens, 9 (9 Pathogens, Vol 9, Iss 722, p 722 (2020) Volume 9 Issue 9 |
| ISSN: | 2076-0817 |
| Popis: | The enormity of the public health burden of onchocerciasis motivated the creation of various large-scale control programs that have depended principally on mass treatment of endemic communities with ivermectin for the elimination of the disease. Parasitological evaluation of Onchocerca species in the West Region of Cameroon indicates significant progress in the interruption of parasite transmission in some communities under ivermectin treatment. However, to verify the complete elimination of onchocerciasis, entomological assessment through O-150 PCR poolscreen of black flies is mandatory. Thus, in the present study, we assessed transmission of Onchocerca species using an O-150 PCR technique to screen pools of black flies&mdash in seven onchocerciasis endemic communities (Makouopsap, Bankambe, Lemgo, Tsesse, Ndionzou, Kouffen, and Bayon) in Cameroon. Two thousand black flies were assessed&mdash in each community&mdash for the presence of Onchocerca species DNA. Our results show that the frequency of infective flies was 0.6% in Makouopsap and 0.0% in the other communities. On the other hand, the frequency of infected flies was 0.8% in Makouopsap, 0.2% in Bankambe, 0.1% in Bayon, and 0.0% in Lemgo, Tsesse, Ndionzou, and Kouffen. These results provide entomologic evidence for continuous transmission of Onchocerca species in Makouopsap, risk of active transmission in Bankambe, and Bayon, and a suppressed transmission in the four other studied communities. |
| Databáze: | OpenAIRE |
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