Estimating the Screening-Eligible Population Size, Ages 45–74, at Average Risk to Develop Colorectal Cancer in the United States
| Autor: | David K Edwards, Andrew Piscitello |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
Male
0301 basic medicine Cancer Research medicine.medical_specialty Colorectal cancer Population Risk Assessment 03 medical and health sciences 0302 clinical medicine Risk Factors Preventive Health Services Humans Medicine Family history education Early Detection of Cancer Aged education.field_of_study Cancer prevention business.industry Population size Public health Age Factors Cancer Guideline Middle Aged medicine.disease United States 030104 developmental biology Oncology 030220 oncology & carcinogenesis Practice Guidelines as Topic Female Colorectal Neoplasms business SEER Program Demography |
| Zdroj: | Cancer Prevention Research. 13:443-448 |
| ISSN: | 1940-6215 1940-6207 |
| Popis: | Colorectal cancer is a growing burden in adults less than 50 years old. In 2018, the American Cancer Society published a guideline update recommending a reduction in the colorectal cancer screening start age for average-risk individuals from 50 to 45. Implementing these recommendations would have important implications for public health. However, the approximate number of people impacted by this change, the average-risk population ages 45–49, is not well-described in the literature. Here, we provide methodology to conservatively estimate the average-risk and screening-eligible population in the United States, including those who would be impacted by a lowered colorectal cancer screening start age. Using multiple data sources, we estimated the current average-risk population by subtracting individuals with symptomatic colorectal cancer, with a family history of colorectal cancer, and with inflammatory bowel disease and hereditary nonpolyposis colorectal cancer from the total population. Within this population, we estimated the number of screening-eligible individuals by subtracting those with previous colorectal cancer screening (45- to 49-year-old) or up to date with colorectal cancer screening (50- to 74-year-old). The total average-risk population is estimated between 102.1 and 106.5 million people, of whom 43.4–45.2 million people are eligible for colorectal cancer screening. Lowering the screening age would add roughly 19 million people to the average-risk population and increase the current number of screening-eligible individuals on immediate implementation by over 60% (from 27 to 44 million). Estimating the population size impacted by lowering the recommended colorectal cancer screening start age enables more accurate decision-making for policymakers and epidemiologists focused on cancer prevention. |
| Databáze: | OpenAIRE |
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