Value of neutrophil-to-lymphocyte ratio as a marker of renal damage in patients with H-type hypertension
Autor: | Si-Jin Li, Wei Chen, Huan Yang, Zhen-Ni Chen, Yi-Ran Huang, Bi-Qiong Ren, Kun Liu, Xing Chen, Zhi-Hong Luo |
---|---|
Rok vydání: | 2021 |
Předmět: |
Male
medicine.medical_specialty Homocysteine Neutrophils Clinical Biochemistry 030232 urology & nephrology Renal function 030204 cardiovascular system & hematology Logistic regression Gastroenterology 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine Risk Factors Internal medicine Drug Discovery Linear regression Humans Medicine Lymphocytes Neutrophil to lymphocyte ratio Blood urea nitrogen Aged Retrospective Studies Creatinine Receiver operating characteristic business.industry fungi Biochemistry (medical) Middle Aged Prognosis ROC Curve chemistry Case-Control Studies Hypertension Female Kidney Diseases business Biomarkers Glomerular Filtration Rate |
Zdroj: | Biomarkers in Medicine. 15:637-646 |
ISSN: | 1752-0371 1752-0363 |
DOI: | 10.2217/bmm-2020-0638 |
Popis: | Aim: To explore the relationship between the neutrophil-to-lymphocyte ratio (NLR) and renal damage in patients with H-type hypertension. Materials & methods: A total of 618 patients between 2017 and 2019 were analyzed retrospectively. Results: NLR was significantly correlated with renal damage in hypertension patients. Appropriate cut-off value for NLR (2.247) was determined by receiver operating characteristic curve; linear regression analysis showed that NLR and estimated glomerular filtration rate, blood urea nitrogen/creatinine has a significant negative correlation in H-type hypertension group (p |
Databáze: | OpenAIRE |
Externí odkaz: |