The role of bupivacaine in early postoperative pain control after lumbar decompression
| Autor: | J B Chadduck, L H Pobereskin, J R Sneyd |
|---|---|
| Rok vydání: | 1999 |
| Předmět: |
Male
medicine.medical_specialty Visual analogue scale medicine.drug_class Decompression Anti-Inflammatory Agents Methylprednisolone Drug Administration Schedule Lumbar Double-Blind Method medicine Humans Prospective Studies Anesthetics Local Pain Measurement Bupivacaine Pain Postoperative Lumbar Vertebrae Local anesthetic business.industry General Medicine Perioperative Middle Aged Surgery Treatment Outcome Anesthesia Morphine Female business medicine.drug |
| Zdroj: | Journal of Neurosurgery: Spine. 90:67-72 |
| ISSN: | 1547-5654 |
| Popis: | Object. The authors studied the effect of immediate postoperative administration of bupivacaine in patients who underwent a lumbar decompressive procedure. Methods. In this randomized double-blind trial, 50 patients who underwent elective lumbar decompression after induction of general anesthetic received a postoperative bilateral paravertebral 40-ml intramuscular application of either saline (0.9%) or bupivacaine (0.25%). For delivering morphine, both groups used a patient-controlled analgesia system for 24 hours postsurgery. Pain scores, 10-cm visual analog scale scores, and morphine consumption were similar between groups with no significant differences (p > 0.05). Conclusions. Results of subgroup analysis suggested strongly that perioperative administration of methylprednisolone in a sustained-release preparation was associated with a reduction in postoperative pain (p < 0.05). |
| Databáze: | OpenAIRE |
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