Quantifying myocardial fibrosis in hypertensive left ventricular hypertrophy using T1 mapping
| Autor: | Christopher M. Kramer, Frederick H. Epstein, Rajesh Janardhanan, Ronny S. Jiji, Michael Salerno, Jeremy Brooks, Nebiyu Adenaw |
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| Jazyk: | angličtina |
| Rok vydání: | 2012 |
| Předmět: |
Volume of distribution
Medicine(all) medicine.medical_specialty Pathology lcsh:Diseases of the circulatory (Cardiovascular) system Radiological and Ultrasound Technology business.industry Gadolinium Hypertensive left ventricular hypertrophy chemistry.chemical_element medicine.disease chemistry Fibrosis lcsh:RC666-701 Internal medicine Poster Presentation Cardiology medicine Radiology Nuclear Medicine and imaging Myocardial fibrosis cardiovascular diseases Cardiology and Cardiovascular Medicine business Angiology Bolus injection |
| Zdroj: | Journal of Cardiovascular Magnetic Resonance, Vol 14, Iss Suppl 1, p P172 (2012) Journal of Cardiovascular Magnetic Resonance |
| ISSN: | 1097-6647 |
| Popis: | Summary Diffuse myocardial fibrosis in hypertensive left ventricular hypertrophy (LVH) is not readily detected by conventional late gadolinium enhanced CMR. Our study was aimed to detect diffuse myocardial fibrosis in these patients as compared to age matched normal controls, using a T1 mapping technique. Fibrosis was quantified by calculating the partition coefficient (l) and volume of distribution (Vd) of gadolinium (Gd) following a bolus injection of Gd. We observed that the values for l and Vd were higher in LVH than controls. A positive association was also noted between LV mass and l. Background |
| Databáze: | OpenAIRE |
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