Cardiovascular fitness in late adolescent males and later risk of serious non-affective mental disorders: a prospective, population-based study
| Autor: | Maria A I Åberg, Jenny Nyberg, Hans-Georg Kuhn, Malin Henriksson, N. D. Åberg, Margda Waern, Mia Söderberg, Annika Rosengren |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
Adult
Male medicine.medical_specialty Adolescent Neurotic Disorders Population Neuropsychological Tests 03 medical and health sciences Young Adult 0302 clinical medicine Risk Factors medicine Humans 030212 general & internal medicine Prospective Studies Psychiatry education Cardiovascular fitness Applied Psychology Depression (differential diagnoses) Proportional Hazards Models Sweden education.field_of_study business.industry Hazard ratio Middle Aged Mental illness medicine.disease Neuroticism Psychiatry and Mental health Military Personnel Cardiorespiratory Fitness Psychotic Disorders Schizophrenia Exercise Test business 030217 neurology & neurosurgery Cohort study Follow-Up Studies |
| Zdroj: | Psychological medicine. 48(3) |
| ISSN: | 1469-8978 0033-2917 |
| Popis: | BackgroundCardiovascular fitness in late adolescence is associated with future risk of depression. Relationships with other mental disorders need elucidation. This study investigated whether fitness in late adolescence is associated with future risk of serious non-affective mental disorders. Further, we examined how having an affected brother might impact the relationship.MethodProspective, population-based cohort study of 1 109 786 Swedish male conscripts with no history of mental illness, who underwent conscription examinations at age 18 between 1968 and 2005. Cardiovascular fitness was objectively measured at conscription using a bicycle ergometer test. During the follow-up (3–42 years), incident cases of serious non-affective mental disorders (schizophrenia and schizophrenia-like disorders, other psychotic disorders and neurotic, stress-related and somatoform disorders) were identified through the Swedish National Hospital Discharge Register. Cox proportional hazards models were used to assess the influence of cardiovascular fitness at conscription and risk of serious non-affective mental disorders later in life.ResultsLow fitness was associated with increased risk for schizophrenia and schizophrenia-like disorders [hazard ratio (HR) 1.44, 95% confidence interval (CI) 1.29–1.61], other psychotic disorders (HR 1.41, 95% CI 1.27–1.56), and neurotic or stress-related and somatoform disorders (HR 1.45, 95% CI 1.37–1.54). Relationships persisted in models that included illness in brothers.ConclusionsLower fitness in late adolescent males is associated with increased risk of serious non-affective mental disorders in adulthood. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|