Mycobacteria-Induced Suppression of Autoimmunity in the Central Nervous System
| Autor: | Zsuzsanna Fabry, Matyas Sandor, Erika Heninger, JangEun Lee |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2010 |
| Předmět: |
Encephalomyelitis
Autoimmune Experimental T-Lymphocytes Immunology Central nervous system Neuroscience (miscellaneous) Biology medicine.disease_cause Article Autoimmunity Mycobacterium Pathogenesis Autoimmune Diseases of the Nervous System Immunity medicine Immunology and Allergy Animals Humans Pharmacology Molecular interactions B-Lymphocytes Interleukin-17 Clinical course Cns autoimmunity Th1 Cells Immunity Innate medicine.anatomical_structure Interleukin 17 |
| Popis: | Mycobacterial suppression of central nervous system (CNS) autoimmunity has been demonstrated in various experimental models, epidemiological studies, and clinical trials. Recent studies have led to an increased understanding of the cellular and molecular interactions involved in the pathogenesis of autoimmune diseases and of mycobacterial immunity. Here, we review some of the mechanisms by which mycobacterial infection might modulate the clinical course of CNS autoimmunity. A more complete understanding of these mechanisms may lead to the development of novel immunotherapeutic tools for treating autoimmune diseases. |
| Databáze: | OpenAIRE |
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