Drug-induced Sialorrhoea
| Autor: | Maija Bruun Haastrup, Daniel Pilsgaard Henriksen, Mette Marie Hougaard Christensen |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
Pharmacology
Drug medicine.medical_specialty business.industry media_common.quotation_subject Treatment options 030227 psychiatry 03 medical and health sciences 0302 clinical medicine medicine Pharmacology (medical) Intensive care medicine Adverse effect business 030217 neurology & neurosurgery Clozapine medicine.drug media_common |
| Zdroj: | Haastrup, M B, Henriksen, D P & Christensen, M M 2018, ' Drug-induced Sialorrhoea ', Adverse Drug Reaction Bulletin, vol. 313, no. 1, pp. 1211–1214 . https://doi.org/10.1097/FAD.0000000000000037 |
| ISSN: | 2159-7774 0044-6394 |
| DOI: | 10.1097/fad.0000000000000037 |
| Popis: | Sialorrhoea is a common adverse effect of a range of medicines, primarily clozapine. At least a third of patients treated with clozapine suffer from sialorrhoea, and the consequences of this can be socially stigmatising and lead to non-adherence. The treatment options are limited and primarily centered around muscarinic antagonism. We suggest non-pharmacological interventions followed by locally applied atropine or glycopyrrolate. If systemic treatment is necessary, amisulpride, benztropine, or terazosin may be attempted. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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