Antibacterial Activity of Hybrid Polymeric Scaffold for Reconstruction of Tubular Bone Defects
| Autor: | D. Yu. Zalepugin, Fedor Senatov, N. Yu. Anisimova, M. V. Kiselevskii, A.V. Maksimkin, I. V. Chernyshova, Alexander Karaulov, S. M. Sitdikova, T. S. Spirina |
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| Rok vydání: | 2019 |
| Předmět: |
0301 basic medicine
Tubular bone Scaffold Materials science Polymers chemistry.chemical_element General Biochemistry Genetics and Molecular Biology 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine polycyclic compounds Polymeric scaffold Porosity Tissue Scaffolds technology industry and agriculture Amoxicillin General Medicine Polyethylene Bactericidal effect Anti-Bacterial Agents 030104 developmental biology Chemical engineering chemistry Polyethylenes Antibacterial activity 030217 neurology & neurosurgery Titanium |
| Zdroj: | Bulletin of Experimental Biology and Medicine. 168:58-61 |
| ISSN: | 1573-8221 0007-4888 |
| DOI: | 10.1007/s10517-019-04646-2 |
| Popis: | We studied antibacterial activity of a hybrid polymeric construction consisting of continuous and porous layers of ultrahigh-molecular-weight polyethylene reinforced by titanium. Experimental samples were impregnated with amoxycillin in subcritical Freon R22. The contact of bacterial culture with hybrid polymeric constructions saturated with amoxycillin suppressed the growth of microorganisms and the formation of their colonies. These results attest to the presence of a bactericidal effect of hybrid scaffold samples impregnated with an antibacterial component. |
| Databáze: | OpenAIRE |
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