Phytochemical study and evaluation of the antimicrobial activity and cytotoxicity of Cuscuta racemosa
| Autor: | Rui A. Carvalho, Magali Glauzer Silva, Edna Tomiko Myiake Kato, Ivana Barbosa Suffredini, Helena O. Ferraz, Fernanda Arakaki, Elfriede Marianne Bacchi |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2011 |
| Předmět: |
chemistry.chemical_classification
antimicrobial activity Traditional medicine biology Parasitic plant Flavonoid lcsh:RS1-441 Brine shrimp medicine.disease_cause biology.organism_classification Antimicrobial Convolvulaceae Microbiology FITOQUÍMICA lcsh:Pharmacy and materia medica chemistry Phytochemical Staphylococcus aureus Cuscuta racemosa medicine Tannin cytotoxicity General Pharmacology Toxicology and Pharmaceutics |
| Zdroj: | Revista Brasileira de Farmacognosia, Vol 21, Iss 1, Pp 41-46 (2011) Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual) Universidade de São Paulo (USP) instacron:USP Revista Brasileira de Farmacognosia, Volume: 21, Issue: 1, Pages: 41-46, Published: 26 NOV 2010 Revista Brasileira de Farmacognosia v.21 n.1 2011 Revista Brasileira de Farmacognosia Sociedade Brasileira de Farmacognosia (SBFgnosia) instacron:SBFGNOSIA Revista Brasileira de Farmacognosia, Vol 21, Iss 1, Pp 41-46 (2010) |
| Popis: | Cuscuta racemosa Mart. is a parasitic plant of the Convolvulaceae family, used in popular medicine as an anti-inflammatory and a diuretic, for stomach and hepatic disorders, and for treating fresh wounds. This plant is popularly known as "cipó-chumbo" and "fios-de-ovos". In this study, it was chemically investigated and tested for its antimicrobial activity and cytotoxicity. The flavonoid and tannin content of the dried plant were 2.79% and 2.01%, respectively. Furthermore, the 4'-methoxyquercetin flavanoid compound was isolated from the ethanolic fraction. The minimum inhibiting concentration in the antimicrobial test was 2.0 mg/ml for Staphylococcus aureus, and a DL50 of 0.231 mg/mL was obtained in the cytotoxicity experiment. The fraction directed to alkaloids was able to eliminate 100% of the brine shrimp used for the test. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|