Antimicrobial properties of biodegradable magnesium for next generation ureteral stent applications
| Autor: | Lock, J. Y., Draganov, M., Whall, A., Dhillon, S., Upadhyayula, S., Vullev, V. I., Huinan Liu |
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| Rok vydání: | 2012 |
| Předmět: |
Surface Properties
medicine.medical_treatment Polyurethanes chemistry.chemical_element Urinary Catheters Biomedical equipment Models Biological Escherichia coli medicine Humans Magnesium Cell Proliferation Stent Ureteral stents Hydrogen-Ion Concentration Biodegradation equipment and supplies Antimicrobial Anti-Bacterial Agents surgical procedures operative Artificial urine chemistry Biodegradable magnesium Stents Ureter Biomedical engineering |
| Zdroj: | EMBC Scopus-Elsevier |
| DOI: | 10.1109/embc.2012.6346195 |
| Popis: | Bacterial infection often causes clinical complications and failure of indwelling medical devices. This is a major problem of current ureteral stents, which are used clinically to treat the blockage of ureteral canals. This study investigates the effectiveness and applicability of magnesium as a novel biodegradable ureteral stent material that has inherent antimicrobial properties. Incubating Escherichia coli with the magnesium samples showed a decrease in the bacterial cell density as compared with the currently used commercial polyurethane stent. Magnesium degradation in the immersion solutions (artificial urine, luria bertani broth, and deionized water) resulted in an alkaline pH shift. Antimicrobial and biodegradation properties of magnesium make it an attractive alternative as next-generation ureteral stent material. |
| Databáze: | OpenAIRE |
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