Role of bowel ultrasound as a predictor of surgical recurrence of Crohn's disease
| Autor: | N. Sapone, A. Resegotti, Antonino Sarno, Rinaldo Pellicano, Davide Giuseppe Ribaldone, Giovanni Bonenti, Alessandro Repici, Francesca Bresso, Paola Debani, Daniela Robotti, Gionata Fiorino, D Simondi, Alida Andrealli, Marco Astegiano, Silvio Danese, Teresa Cammarota |
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| Přispěvatelé: | Cammarota, T, Ribaldone, Dg, Resegotti, A, Repici, A, Danese, S, Fiorino, G, Sarno, A, Robotti, D, Debani, P, Bonenti, G, Pellicano, R, Andrealli, A, Sapone, N, Simondi, D, Bresso, F, Astegiano, M |
| Rok vydání: | 2013 |
| Předmět: |
Adult
Male Reoperation medicine.medical_specialty Adolescent Colon Anastomosis Young Adult Crohn Disease Ileum Recurrence Risk Factors Colon surgery Humans Medicine Risk factor Aged Retrospective Studies Ultrasonography Aged 80 and over Crohn's disease Post-surgical recurrence business.industry Incidence Bowel ultrasonography Medicine (all) Ultrasound Gastroenterology Retrospective cohort study Middle Aged medicine.disease Confidence interval Surgery Relative risk Female business Follow-Up Studies |
| Popis: | In Crohn's disease natural history, about 80% of the patients require surgery, which is not curative: unfortunately, the disease recurs in many patients.To investigate the role of intestinal ultrasound to predict the risk of post-operative surgical recurrence in Crohn's disease.A total of 196 patients, with ileal or ileocolonic Crohn's disease, undergoing intestinal resection, were retrospectively enrolled. All patients underwent bowel ultrasonography 6-15 months after resection. Wall thickness at the anastomosis level was measured, and thickening3 mm was evaluated as risk factor of long-term need for reoperation.Patients who have a bowel wall thickness3 mm have an risk ratio (RR) of surgical recurrence = 2.1 [95% confidence interval (CI) = 1.12-3.74] higher than those with a thickness of ≤3 mm. The absolute incidence of new surgical intervention is 13% in patients with thickness of 3 mm, 28% in patients with thickness3 mm, 29,1% with thickness4 mm, 34% with thickness5 mm, and 40% with thickness6 mm.Bowel wall thickness3 mm at ultrasound may be a non-invasive predictor of early surgical recurrence after ileo-colonic resection. |
| Databáze: | OpenAIRE |
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