Phase II multiclinic study of elantrine in parkinsonism

Autor:	E. Richard Blonsky, Alexander S. McKinney, Arthur Dale Ericsson, Alfred A. Rimm, Alvin Rix, Richard I. H. Wang
Rok vydání:	1974
Předmět:	Male Pharmacology Clinical Trials as Topic Trihexyphenidyl business.industry Parkinsonism Parkinson Disease Placebo period medicine.disease Muscle Rigidity Antiparkinson Agents Dibenzazepines Anesthesia Tremor Humans Medicine Female Pharmacology (medical) business Dimethylamines Aged medicine.drug
Zdroj:	Clinical Pharmacology & Therapeutics. 15:46-50
ISSN:	0009-9236
DOI:	10.1002/cpt197415146
Popis:	A cooperative controlled study comparing elantrine with trihexyphenidyl and a baseline placebo period demonstrates definite lessening of tremor severity during elan trine treatment and a statistically significantly greater reduction in tremor compared to trihexyphenidyl. Effectiveness in alleviating rigidity and akinesia was less but similar to trihexyphenidyl.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1e33192ecbc7780b933ac76e3f5ed2b https://doi.org/10.1002/cpt197415146 Zobrazit plný text záznamu