Analysis of clinical characteristic and risk factors for short-term prognosis of moyamoya disease with intraventricular hemorrhage in adults

Autor: Pengfei Tong, Tikun Shan, Jiyang An, Shuang Liu, Gehan Jing, Jiajia Bi, Zhengfeng Wang
Rok vydání: 2022
Předmět:
Zdroj: World neurosurgery.
ISSN: 1878-8769
Popis: Intraventricular hemorrhage is the most common type of hemorrhage in moyamoya disease (MMD) with intracerebral hemorrhage (ICH), but the risk factors affecting the short-term prognosis of MMD with intraventricular hemorrhage (IVH) in adults are still unclear.We retrospectively analyzed patients of MMD with IVH between January 1, 2018 and January 31, 2020 in the First Affiliated Hospital of Zhengzhou University. According to the mRS score at 3 months after discharge, the patients were divided into mRS≤2 (good prognosis) group and mRS2 (poor prognosis) group. Univariate and multivariate Logistics regression analysis were used to analyze the risk factors affecting the short-term prognosis of adult MMD with IVH.Univariable analyses showed that patients in the poor prognosis group had a significantly older age of onset (48.48±8.34 vs 43.74±5.44, p=0.002), a higher percentage of hypertension (57.97% vs 33.33%, p=0.014), a higher percentage of tracheotomy (23.19% vs 2.56%, p=0.005), a lower GCS score (7.90±3.58 vs 11.19±2.56, p=0.000), a higher Graeb score (7.46±4.04 vs 5.23±1.93, p=0.002), and treatment methods (p=0.000). Multiple logistic regression analysis revealed that the lower GCS score (OR=1.761, p=0.001) and higher Graeb score (OR=1.767, p=0.002) were independently associated with the poor prognosis of MMD with IVH, and surgery treatment (OR=0.032, p=0.000) was independently related to the good prognosis of MMD with IVH.Among MMD with IVH patients, the lower GCS score and higher Graeb score are independent risk factors for the poor prognosis, while a MMD with IVH patient with surgery treatment acts as a protective factor.
Databáze: OpenAIRE