Assessment of a conventional volumetric-modulated arc therapy knowledge-based planning model applied to the new Halcyon© O-ring linac in locoregional breast cancer radiotherapy
| Autor: | Christel Bragard, M. Robilliard, Alain Fourquet, Youlia M. Kirova, E. Costa, Ludovic De Marzi, Christelle Logerot, Thomas Richir |
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| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
Knowledge based planning Computer science medicine.medical_treatment Biophysics General Physics and Astronomy Breast Neoplasms Breast cancer radiotherapy Linear particle accelerator 030218 nuclear medicine & medical imaging 03 medical and health sciences 0302 clinical medicine Breast cancer medicine Arc therapy Humans Radiology Nuclear Medicine and imaging Medical physics Radiotherapy Planning Computer-Assisted Radiotherapy Dosage General Medicine medicine.disease Volumetric modulated arc therapy Target dose Radiation therapy 030220 oncology & carcinogenesis Female Radiotherapy Intensity-Modulated Particle Accelerators |
| Zdroj: | Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB). 86 |
| ISSN: | 1724-191X |
| Popis: | Introduction The aim of this study was to evaluate the performance of a knowledge-based planning (KBP) model for breast cancer trained on plans performed on a conventional linac with 6 MV FF (flattening filter) beams and volumetric-modulated arc therapy (VMAT) for plans performed on the new jawless Halcyon© system with 6 MV FFF (flattening filter-free) beams. Materials and methods Based on the RapidPlan© (RP) KBP optimization engine, a DVH Estimation Model was first trained using 56 VMAT left-sided breast cancer treatment plans performed on a conventional linac, and validated on another 20 similar cases (without manual intervention). To determine the capacity of the model for Halcyon©, an additional cohort of 20 left-sided breast cancer plans was generated with RP and analyzed for both TrueBeam© and Halcyon© machines. Plan qualities between manual vs RP (followed by manual intervention) Halcyon© plans set were compared qualitatively by blinded review by radiation oncologists for 10 new independent plans. Results Halcyon© plans generated with the VMAT model trained with conventional linac plans showed comparable target dose distribution compared to TrueBeam© plans. Organ sparing was comparable between the 2 devices with a slight decrease in heart dose for Halcyon© plans. Nine out of ten automatically generated Halcyon© plans were preferentially chosen by the radiation oncologists over the manually generated Halcyon© plans. Conclusion A VMAT KBP model driven by plans performed on a conventional linac with 6 MV FF beams provides high quality plans performed with 6 MV FFF beams on the new Halcyon© linac. |
| Databáze: | OpenAIRE |
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