The acid mucopolysaccharides in normal urine
| Autor: | David P. Varadi, J.A. Cifonelli, Albert Dorfman |
|---|---|
| Rok vydání: | 1967 |
| Předmět: |
Electrophoresis
Male Chromatography Paper Biophysics Glycine Chondroitin sulfate B Hyaluronoglucosaminidase Urine Biochemistry Glycosaminoglycan chemistry.chemical_compound Sulfation Glutamates Polysaccharides Serine Chondroitin Humans Chondroitin sulfate Sulfate Hyaluronic Acid Molecular Biology Glycosaminoglycans Chromatography Chemistry Sulfates Chromatography Ion Exchange Uronic Acids Chromatography Gel Peptides |
| Zdroj: | Biochimica et biophysica acta. 141(1) |
| ISSN: | 0006-3002 |
| Popis: | 1. 1. The purpose of this investigation is to report the qualitative distribution of acid munopolysaccharides in normal urine and the composition of a mucopeptide isolated from urine. 2. 2. The predominant mucopolysaccharides in normal urine are a family of chondrotin sulfates characterized by a varying sulfate content. Chondroitin sulfate A and chondroitin sulfate C each constitute about one-third of the total mucopolysaccharide, while chondroitin (non-sulfated chondroitin sulfate) constitutes one-fourth of the total mucopolysaccharide. 3. 3.Heparitin monosulfate makes up approx. 8% of the total mucopolysaccharide excreted. Hyaluronic acid, chondroitin sulfate B, and a highly sulfated keratosulfate are excreted in trace amounts. 4. 4. Monosulfated chrondroitin sulfate, as found in normal urine, is extracted as fragments of small molecular size, some of which are covalently bound to a polypeptide characterized by a high serine, glycine and glutamic acid content. |
| Databáze: | OpenAIRE |
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