Hospital-acquired intestinal toxemia botulism in a newly diagnosed adult colon cancer patient
| Autor: | Diogo C. Carvalho, Gil Pereira Neto, Helena Providelli de Moraes, Breno Franco Silveira Fernandes, Izabela Dayany França Feitosa, Vandack Nobre, Lucas José Sá da Fonseca, Rodrigo Santiago Gomez, Rodrigo Vasconcellos Vilela |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
medicine.medical_specialty
lcsh:Arctic medicine. Tropical medicine Flaccid paralysis lcsh:RC955-962 Colorectal cancer medicine.drug_class 030231 tropical medicine Antibiotics Botulinum Antitoxin Neuromuscular junction Case Report medicine.disease_cause 03 medical and health sciences 0302 clinical medicine Internal medicine Diagnosis Symmetrical descending flaccid paralysis Clostridium botulinum Medicine Botulism Adult intestinal toxemia botulism business.industry medicine.disease Neuropathy Infectious disease (medical specialty) Intestinal colonization medicine.symptom Differential diagnosis business |
| Zdroj: | Revista do Instituto de Medicina Tropical de São Paulo; Vol. 61 (2019); e49 Revista do Instituto de Medicina Tropical de São Paulo; v. 61 (2019); e49 Revista do Instituto de Medicina Tropical de São Paulo Instituto de Medicina Tropical (IMT) instacron:IMT Revista do Instituto de Medicina Tropical de São Paulo, Vol 61 |
| ISSN: | 1678-9946 0036-4665 |
| DOI: | 10.1590/s1678-9946201961049 |
| Popis: | This manuscript reports a case of intestinal toxemia botulism in an adult with recently diagnosed metastatic colon cancer in whom botulism symptoms began 23 days after hospital admission. Representing the rarest form of botulism presentation in clinical practice, this infectious disease may have developed due to a cluster of predisposing factors that favored Clostridium botulinum colonization and the endogenous production of neurotoxins, among which are previous use of broad-spectrum antibiotics and colon changes related to the development of the neoplasia. This case highlights the importance of considering intestinal toxemia botulism in the differential diagnosis of a patient presenting with symmetrical descending flaccid paralysis, since immediate treatment with botulinum antitoxin may improve clinical outcomes. |
| Databáze: | OpenAIRE |
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