Status for clinically complete remission rectal cancer after concomitant chemo-radiotherapy in Taiwan
| Autor: | Chun-Ju Chiang, Jeng Yi Wang, Jinn Shiun Chen, Kuan Der Lee, Chien Yuh Yeh, Geng Ping Lin |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: |
Adult
Male medicine.medical_specialty Colorectal cancer Treatment outcome Taiwan lcsh:Surgery Intervention group 03 medical and health sciences 0302 clinical medicine medicine Overall survival Humans Aged Retrospective Studies Aged 80 and over Chemo-radiotherapy business.industry Rectal Neoplasms Complete remission Rectum Chemoradiotherapy Adjuvant lcsh:RD1-811 Middle Aged medicine.disease Survival Analysis Neoadjuvant Therapy Surgery Treatment Outcome 030220 oncology & carcinogenesis Concomitant Local recurrence free survival 030211 gastroenterology & hepatology Female Neoplasm Recurrence Local business Follow-Up Studies |
| Zdroj: | Asian Journal of Surgery, Vol 41, Iss 3, Pp 203-209 (2018) |
| ISSN: | 1015-9584 |
| Popis: | Summary: Treatment for Rectal cancer changed after the induction of concomitant chemo-radiotherapy, CCRT. Complete remission of the tumor leads to debate of the necessity of surgical intervention. We evaluate the treatment outcome to know if operation is beneficial to these patients. Patients received long course concomitant chemo-radiotherapy for advanced rectal cancer between 2004 and 2013 in Taiwan were enrolled. Total 2780 patients diagnosed advanced rectal cancer were enrolled. In these patients, 2578 received surgical intervention and 202 were in wait and see for complete remission tumor. Higher local recurrence rate was found with wait and see group (8.9% vs. 2.7%). Also, better overall survival, disease free survival and local recurrence free survival were seen with the surgical intervention group. Surgical intervention may be benefit for some misdiagnosed completed response to CCRT. Keywords: Rectal cancer, Complete remission, Long course CCRT, Watch and wait |
| Databáze: | OpenAIRE |
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