Prognostic Role of Serum Albumin Level in Patients with Lymphoma Undergoing Autologous Stem Cell Transplantation
| Autor: | Xi Li, Qingrong Li, Jieping Chen, Yali Zhang, Yanni Sun, Xiangtao Huang, Yarui Huang, Yanni Ma, Zhen Huang, Chengxin Luo, Mingling Xie, Shuangnian Xu, Guixian Wu |
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| Rok vydání: | 2021 |
| Předmět: |
Oncology
medicine.medical_specialty Lymphoma Survival medicine.medical_treatment Serum Albumin Human Hematopoietic stem cell transplantation Transplantation Autologous Autologous stem-cell transplantation Maintenance therapy Albumins Internal medicine Humans Medicine Risk factor Retrospective Studies Original Paper Transplantation Chemotherapy business.industry Hematopoietic Stem Cell Transplantation Retrospective cohort study General Medicine Middle Aged Prognosis medicine.disease business |
| Zdroj: | Annals of Transplantation |
| ISSN: | 2329-0358 |
| DOI: | 10.12659/aot.933365 |
| Popis: | Background High-dose chemotherapy followed by autologous stem cell transplantation (HDT/ASCT) plays a crucial role in the therapy of patients with lymphoma. This retrospective study aimed to analyze prognostic factors in patients undergoing HDT/ASCT for lymphoma. Material/Methods We included patients with lymphoma who underwent HDT/ASCT at our center. Time-to-event outcomes, including progression-free survival (PFS) and overall survival (OS), were analyzed with the Kaplan-Meier method and log-rank test. Receiver operating characteristic (ROC) curve analysis and Cox proportional hazard regression analysis were performed to explore the prognostic value of different factors. Results A total of 113 patients with lymphoma were included. Patients with low serum albumin levels (60 years (HR 2.92, 95% CI 1.27–6.71; P=0.012) were independent risk factors for PFS. Total protein |
| Databáze: | OpenAIRE |
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