Single nucleotide polymorphisms as tools in human genetics

Autor:	Nigel K. Spurr, Ian C. Gray, David A. Campbell
Rok vydání:	2000
Předmět:	Genetics Genotype Genome Human Genetics Medical Single-nucleotide polymorphism General Medicine Biology Tag SNP Polymorphism Single Nucleotide Genome Human genetics SNP genotyping Humans Human genome Molecular Biology Genotyping Genetics (clinical) Genetic association
Zdroj:	Human Molecular Genetics. 9:2403-2408
ISSN:	1460-2083
DOI:	10.1093/hmg/9.16.2403
Popis:	The development of detailed single nucleotide polymorphism (SNP) maps of the human genome coupled with high-throughput genotyping technologies may allow us to unravel complex genetic traits, such as multifactorial disease or drug response, over the next few years. Here we describe the current efforts to identify and characterize the large numbers of SNPs required and discuss the practicalities of association studies for the identification of genes involved in complex traits.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1cdcad1c72075986e885fcb93d1e726 https://doi.org/10.1093/hmg/9.16.2403 Zobrazit plný text záznamu