An Approach to Optically Pure Bridging Chiral p-tert-Butylcalix[4]arenes through a Homologous Anionic Ortho-Fries Rearrangement

Autor:	Shi-Kun Ma, Wen-Shan Liu, Jing Guo, Wen-Qiang Xu, Run-Ling Wang, Jiu-Xing Yan, Jun-Min Liu, Shao-Yong Li
Rok vydání:	2016
Předmět:	Bridging (networking) 010405 organic chemistry Stereochemistry Fries rearrangement Chemistry Organic Chemistry Enantiomer 010402 general chemistry 01 natural sciences Medicinal chemistry 0104 chemical sciences
Zdroj:	The Journal of Organic Chemistry. 81:10683-10687
ISSN:	1520-6904 0022-3263
DOI:	10.1021/acs.joc.6b01682
Popis:	A novel efficient approach to optically pure bridging chiral calix[4]arenes through a homologous anionic ortho-Fries rearrangement of inherently chiral calix[4]arenes was presented for the first time. As a result, two pairs of N,N'-dimethylformamidyl-substituted bridging chiral p-tert-butylcalix[4]arene enantiomers were facilely obtained. Their absolute configurations were determined through ROESY analysis, ECD comparison, and X-ray crystallographic analysis.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1b2b9b78bbca953167e9baf6274ef60 https://doi.org/10.1021/acs.joc.6b01682 Zobrazit plný text záznamu