Hematemesis due to Drug Allergy to Oral Prednisolone in a Patient with Ulcerative Colitis
| Autor: | Kazuhiro Takenaka, Hideyuki Hiraishi, Osamu Arisaka, Fumiaki Takahashi, Keiichi Tominaga, Atsushi Irisawa, Takahiro Arisaka, Takeshi Sugaya, Mimari Kanazawa |
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| Rok vydání: | 2019 |
| Předmět: |
Adult
Male medicine.medical_specialty Allergy Prednisolone Drug allergy Anti-Inflammatory Agents Administration Oral Case Report 030204 cardiovascular system & hematology Gastroenterology Tacrolimus Drug Hypersensitivity 03 medical and health sciences 0302 clinical medicine Internal medicine Remission Induction Therapy Internal Medicine medicine Humans Mesalamine ulcerative colitis medicine.diagnostic_test Esophagogastroduodenoscopy business.industry Remission Induction Hematemesis General Medicine medicine.disease Ulcerative colitis Bloody Treatment Outcome drug lymphocyte stimulation test Colitis Ulcerative 030211 gastroenterology & hepatology business drug allergy medicine.drug |
| Zdroj: | Internal Medicine |
| ISSN: | 1349-7235 0918-2918 |
| DOI: | 10.2169/internalmedicine.1639-18 |
| Popis: | The patient was diagnosed with ulcerative colitis and received remission induction therapy with prednisolone. While they developed muscle pain in the lower extremities after starting prednisolone, they ultimately achieved clinical remission. After discharge, hematemesis and gastric discomfort developed. Esophagogastroduodenoscopy showed mucosal edema, redness, and oozing bleeding in the gastric body. In addition, the patient had bloody stool and was considered to have a relapse of ulcerative colitis. They therefore received remission induction therapy with tacrolimus. The patient achieved clinical remission again; however, gastric discomfort and muscle pain remained. A drug lymphocyte stimulation test revealed positivity for prednisolone; therefore, the patient was diagnosed with an allergy to prednisolone. |
| Databáze: | OpenAIRE |
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