Trajectories and predictors of symptom occurrence, severity, and distress in prostate cancer patients undergoing radiation therapy
| Autor: | Katie Knapp, Theresa Koetters, Anand Dhruva, Bruce A. Cooper, Bradley E. Aouizerat, Claudia West, Christine Miaskowski, Janine K. Cataldo, Steven M. Paul |
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| Rok vydání: | 2012 |
| Předmět: |
Male
Aging medicine.medical_treatment severity Severity of Illness Index radiation therapy Medical and Health Sciences Prostate cancer Quality of life Anesthesiology Longitudinal Studies General Nursing Fatigue Cancer media_common Pain Research Middle Aged Distress symptom trajectories Chronic Pain Symptom Assessment Urologic Diseases medicine.medical_specialty media_common.quotation_subject Pain Context (language use) Affect (psychology) occurrence Urination Article Clinical Research Internal medicine Severity of illness medicine Humans Aged Radiotherapy business.industry Prostatic Neoplasms distress medicine.disease Radiation therapy symptom predictors Anesthesiology and Pain Medicine piecewise modeling Physical therapy Quality of Life Neurology (clinical) business |
| Zdroj: | Journal of pain and symptom management, vol 44, iss 4 Knapp, K; Cooper, B; Koetters, T; Cataldo, J; Dhruva, A; Paul, SM; et al.(2012). Trajectories and predictors of symptom occurrence, severity, and distress in prostate cancer patients undergoing radiation therapy. Journal of Pain and Symptom Management, 44(4), 486-507. doi: 10.1016/j.jpainsymman.2011.10.020. UCSF: Retrieved from: http://www.escholarship.org/uc/item/6b72k1tb |
| Popis: | Context. Radiation therapy (RT) is a common treatment for prostate cancer. Despite available research, prostate cancer patients report that information about side effects is their most important unmet need. Additional research is needed that focuses on specific dimensions of the patient's symptom experience. Objectives. The study's purposes were to evaluate the trajectories of occurrence, severity, and distress of the six most prevalent symptoms reported by patients undergoing RT for prostate cancer and the effects of selected demographic and clinical characteristics on these trajectories. Methods. Patients completed the Memorial Symptom Assessment Scale 11 times before, during, and after RT. For problems with urination, pain, lack of energy, feeling drowsy, difficulty sleeping, and diarrhea, the trajectories of occurrence, severity, and distress were evaluated using multilevel generalized linear models. Results. Across all three dimensions, pain, lack of energy, feeling drowsy, and difficulty sleeping followed a decreasing linear trend. Problems with urination and diarrhea demonstrated more complex patterns of change over time. Conclusion. Although longitudinal data on pain, lack of energy, feeling drowsy, and difficulty sleeping are limited, they are highly prevalent symptoms in these patients. In addition, diarrhea becomes a significant problem for these patients over the course of RT. A number of demographic and clinical characteristics affect the trajectories of these common symptoms differentially. © 2012 U.S. Cancer Pain Relief Committee. |
| Databáze: | OpenAIRE |
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